DOTR' Featured dCO₂ Measurement System for Perfusion Monitoring

This small CO₂ meter fits in any measurement set-up. CO₂-1 SMA is compatible with dipping probes, flow-through cells and non-invasive CO₂ sensor spots of type CD1 (measurement range 1 - 25 % CO₂). It has temperature compensation, so even in environments with changing temperatures precise CO₂ measurements can be performed. This USB-powered CO₂ meter is operated with the DOTR Measurement Studio 2 software, which enables simultaneous control of several devices and combination with DOTR O₂ and pH meters, so measurement networks can be set up. With numerous features and additional pressure compensation, the software makes the CO₂-1 SMA applicable in many applications. Optionally, the CO₂-1 SMA can be expanded with 4 - 20 mA analog output (via a converter box).

A polymer optical fiber (POF) is needed to transfer excitation light to single-use flow-through cells (FTC-SU) or sensor sticks (SST) and the signal response back to the meter. For our FTC-SU and SST these special POFs show tight fitting fibers to ensure reliable non-invasive and non-destructive measurements. They are available in two different lengths (2.5 or 5 m) for all meters with an SMA connector as e. g. Fibox, OXY-SMA, OXY mini and pH-SMA series, as well as the CO2-SMA series.

A miniaturized optical CO₂ sensor, immobilized on the distal end of a color-coded polycarbonate Luer adapter, is inserted in a polycarbonate T-cell with 1/8" lumen (0.3 mL volume). The sensor stick can be transferred under laminar flow to alternative FTCs e.g. with larger lumen, if they carry at least one Luer connector. The FTC-SU-CD1-09NaCl-S is ideally suited for measurements in media with physiological osmolality, e.g. in perfusion bioreactors for tissue engineering, or other culture monitoring applications. A polymer optical fiber connects the sensor inside the FTC to the CO₂ meter. The cell is delivered beta-irradiated (> 25 kGy) in physiological saline solution to prevent the sensor to dry. The FTC-SU-CD1-09NaCl-S is compatible to the CO2-1 SMA. In combination with the DOTR Measurement Studio 2 software multiparameter monitoring together with single-use oxygen and pH flow-through cells can be performed.